P250 vs USP-S
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Damage
The P250 deals more damage (21) than the USP-S (16).
The P250 fires faster (400 RPM) than the USP-S (352 RPM).
The P250 deals more damage per second (140) than the USP-S (94).
The P250 loses more damage due to distance (9.6 %) than the USP-S (8.7 %).
The P250 has higher armour penetration (64 %) than the USP-S (50.5 %).
Accuracy and mobility
The P250 is less accurate (11.1) than the USP-S (6.4).
The P250 has the same movement penalty (4 %) as the USP-S (4 %).
Economy
The P250 is more expensive ($ 300) than the USP-S ($ 200).
The P250 earns the same kill reward ($ 300) as the USP-S ($ 300).
Other attributes
The P250 has a larger clip (13) than the USP-S (12).
The P250 has more ammunition in reserve (26) than the USP-S (24).
The P250 reloads slower (2.3 s) than the USP-S (2.2 s).
The P250 deploys at the same speed (1 s) as the USP-S (1 s).
Closing thoughts
At only $300, the P250 is a solid pistol upgrade that gives you more damage and armour penetration at the expense of accuracy.
The USP-S is one of the free starting pistol options for the Counter-Terrorist team. More frequently used than the P2000, it comes with a silencer in exchange for an extra bullet. In any case, it performs better than the Terrorist default.
Right clicking allows the player to remove the silencer, but this just makes the weapon slightly less accurate (and louder of course).